Missouri State University

Graduate College

2013-14 Graduate Catalog

Preliminary Edition
published April 2013

Department of Biomedical Sciences

Professional Building, Room 400, Phone: (417) 836-5603, Fax: (417) 836-5603
Email: BiomedicalSciences@missouristate.edu
Website: http://www.missouristate.edu/bms/
Department Head: Colette M. Witkowski

Graduate faculty

Professor:  Richard C. Garrad, Benjamin F. Timson, Colette M. Witkowski

Associate Professor:  Robert K. DeLong, Scott D. Zimmerman

Assistant Professor:   Amanda C. Brodeur, Anne Marie B. Hunter, Sockju Kwon, Robert T. Morris, Joshua Smith, Jianjie Wang

Program Director, Nurse Anesthesia:  Monika Feeney, CRNA

Assistant Program Director, Nurse Anesthesia: Kathleen D. Fisher, CRNA

Clinical Coordinator, Nurse Anesthesia:  Monika Feeney, CRNA

Instructor:  Natalie Allen, Carmen Boyd, Tracy Beckham, Hillary L. Roberts

Clinical Adjunct Faculty:  Dennis Bray, Charlette Hutsell, Beverly J. Long, Donna Witsberger

Emeritus Professor:  Harold B. Falls, Jr., Christopher C. Field, Albert R. Gordon, Joanne M. Gordon, Harley E. Mortensen

Programs

Master of Science in Cell and Molecular Biology

Scott D. Zimmerman, Director of Graduate Studies
Professional Building, Room 352
Phone (417) 836-5478; ScottZimmerman@missouristate.edu  

Program Description

The graduate program in Cell and Molecular Biology is designed for students preparing for entry into doctorate or health professional programs, or for expanding career opportunities in the biotechnology, biopharmaceutical, health science research, bioinformatics, and genomics sectors. The program offers students with biological or biochemical preparation to increase knowledge in the molecular biosciences and provides initial or additional experiences using the biotechnologies emerging from the rapidly-growing disciplines in cell and molecular biology.  The development of laboratory research skills occurs in a laboratory-focused curriculum that has a health and human emphasis.

Program Objectives 
  1. To educate students at the graduate level in modern concepts and methodologies of cell and molecular biology.
  2. To build upon the student’s foundation of knowledge in cell and molecular biology through enhanced exposure to course, laboratory, and research opportunities.
  3. To enhance the student’s ability to carry out independent research in cell and molecular biology.
Accelerated Master's Degree Option

Majors in cell and molecular biology may be accepted into the Master of Science in Cell and Molecular Biology program after admission requirements for the accelerated master’s option are met.  Once accepted for early admission, up to 12 credit hours of approved 600 and 700-level coursework may be counted toward both the Bachelor of Science and the Master of Science degree programs.  Other required 600-level courses in the master’s program that are taken by the undergraduate student, but not included in the accelerated option, may be waived on the master’s degree program by the student’s graduate advisor if the required courses were taken less than four years previously and the student earned at least a grade of B or better in those courses.  Additional graduate coursework to replace waived courses may be needed to meet the 32 hours degree requirement.  Accelerated option students must enroll in BMS 730 each semester. 

The accelerated option allows cell and molecular biology majors who are interested in biomedical research to complete the requirements for the Master of Science degree in two semesters and a summer rather than the typical four semesters and a summer.  Contact the program director in the Department of Biomedical Sciences for information and guidelines.

Before enrolling in each course to be counted as both undergraduate and graduate credit, an undergraduate student must be accepted into the accelerated program and complete a mixed credit form.  Acceptance into the program and all approvals must be completed prior to the end of the Change of Schedule Period for the course(s).  See the Graduate College for further information.

Admission Requirements for the Accelerated Master’s Option

  1. Junior standing and an overall GPA of 3.40 or better
  2. Completion of BMS 110, 231, 321; CHM 160, 170, 175, 310 with a GPA of 3.40 or better 
  3. Undergraduate laboratory research experience is strongly recommended before applying
  4. Applicants must submit:

a.  an official transcript including all undergraduate work

b.  three letters of recommendation, one written by the future graduate advisor formally accepting the student into their research laboratory.

c.  GRE scores

d.  a statement of research interest

 5.  Acceptance of the applicant by the graduate faculty in cell and molecular biology under the accelerated master’s option

Entrance Requirements

Admission to the program requires a strong science and mathematics background identical to that required of a student completing the undergraduate program in cell and molecular biology.  In addition, admission to the program requires evidence that the applicant will be able to successfully complete a rigorous graduate program in the sciences at a high level of performance.  Entrance into the program requires completion of the following.

  1. Two semesters of organic chemistry
  2. Two semesters of physics
  3. A course in calculus
  4. A bachelor's degree from a Missouri State University recognized accredited college or university and a grade point average (GPA) of at least 3.00 on a 4.00 scale, overall, or for the last 60 hours  
  5. Applicants must have:

a.  an official transcript including all undergraduate work

b.  three letters of recommendation

c.  GRE scores

d.  a statement of research interest

Applicants will be evaluated for admission based upon their submitted materials.  By the end of the first semester, candidates must be accepted into a research laboratory by a member of the Graduate Faculty who becomes the student's advisor

Degree Requirements

The program requires completion of a minimum of 32 semester hours and includes the following.

  1. Core Courses.  This requirement is met by completing:
    BMS 622   Molecular Cell Biology                         4 hrs
    BMS 625   Molecular Biology                                4 hrs
    BMS 658   Recombinant DNA Technology          3 hrs
  2. Orientation.  The candidate must enroll in BMS 701, Research in the Biomedical Sciences (3 hrs).
  3. Signal Transduction.  The candidate must enroll in BMS 635, Signal Transduction (2 hrs).
  4. Statistics.  The candidate must enroll in an approved introductory statistics course at the graduate level if a course in statistics is not a part of their previous academic record.
  5. Electives.  Other remedial or elective courses will be selected by the advisor in consultation with the student.  Up to nine hours of appropriate course work, excluding research and thesis, may be selected from outside the Department of Biomedical Sciences.
  6. Research.  All candidates (thesis and non-thesis options) must satisfactorily complete a research requirement of at least 3 hours by enrolling in BMS 798.  Thesis option candidates may apply an additional 3 hours of BMS 798 and a maximum of 6 hours of BMS 799 toward the 700-level requirement for the degree.  Non-thesis option candidates may not apply more than 4 hours of BMS 798 and may not apply BMS 799 toward the degree.
  7. 700-level courses.  At least 16 hours of course work must be 700 level or above.  A maximum of 6 hours in BMS 798, Research and 6 hours in BMS 799, Thesis may be counted toward the degree. In addition, candidates will be required to enroll every semester in the journal topics course, BMS 730, Current Literature Topics, for a maximum of 4 semesters.
  8. Comprehensive Examination.  The candidate must pass a written exam taken in the third semester of graduate study and an oral examination administered by the departmental cell and molecular biology graduate faculty.
  9. Students must earn at least a C grade in all courses.  Any grade of less than C will result in the dismissal of the student from the program.

Master of Science in Nurse Anesthesia

Benjamin Timson, Academic Advisor of the Nurse Anesthesia Program
Professional Building Room 407;
Phone (417) 836-4145 BenTimson@missouristate.edu

Monika Feeney, CRNA, Program Director of the Nurse Anesthesia Program
St. John’s School of Nurse Anesthesia at Missouri State University;
Phone (417) 820-6890 or MonikaFeeney@missouristate.edu

Kathleen D. Fisher, CRNA, Assistant Program Director of the Nurse Anesthesia Program
St. John’s School of Nurse Anesthesia at Missouri State University;
Phone (417) 820-6890 or KDFisher@missouristate.edu

Program Description

St. John’s School of Nurse Anesthesia at Missouri State University provides the scientific foundation and clinical training that prepares practitioners as certified registered nurse anesthetists (CRNA).

Program Accreditation

St. John’s School of Nurse Anesthesia at Missouri State University is fully accredited by the Council on Accreditation of Nurse Anesthesia Educational Programs, the official accrediting agency for nurse anesthetists.  They may be contacted at 222 South Prospect Avenue, Park Ridge IL 60068; Ph: 847-692-7050.

Entrance Requirements

All applicants must meet the following requirements:

  1. A bachelor's degree in an area of life sciences, nursing, or chemistry from an accredited institution in the U.S. or equivalent training in a foreign university
  2. Undergraduate work must include inorganic chemistry (4 hrs), organic chemistry (4 hrs), microbiology, human anatomy, human physiology; and genetics (strongly recommended)
  3. A minimum GPA of 3.00 on a 4.00 scale for the last 60 hours of undergraduate course work.  Emphasis will be placed on science courses
  4. Submission of official Graduate Record Examination (GRE) scores taken no earlier than five years prior to application with a preferred minimum score of 153 in Verbal Reasoning, 150 in Quantitative Reasoning, and 3.5 in Analytical Writing
  5. Current licensure as a registered nurse in the U.S.
  6. A minimum of one year experience in an acute care setting is required; preferences may be given to applicants with more experience.  Contact the clinical program director regarding questions about appropriate nursing experience
  7. BLS, ACLS, PALS certification are required
  8. A personal interview with a screening committee
  9. The application deadline for the fall and spring semesters are November 1 and July 1, respectively.  Interviews are scheduled within three months after the application deadline
  10. Students admitted into the program will be required to undergo a criminal background check before matriculation
  11. Upon acceptance to the program, the student will pay $100.00 to the AANA for an associate membership (American Associate of Nurse Anesthetists) 
Degree Requirements
    1. Students accepted into the program but who have not previously completed clinical training through an accredited clinical program in nurse anesthesia are required to complete 66 credit hours, which must be in residence.  Students who have completed clinical training in nurse anesthesia and who have passed the national certification examination for nurse anesthesia (CRNAs) but who have not completed an appropriate master’s degree must complete at least 33 credit hours in residence.
    2. Core Course Requirements                         Total   24-25 hrs               
Course CodeCourse TitleCredit Hours
BMS 700 Introduction to Graduate Studies in the Biomedical Sciences 3 hrs
BMS 620 Medical Cell Biology OR 3 hrs
BMS 622 Molecular Cell Biology 4 hrs
BMS 665 Human Cardiopulmonary Physiology 3 hrs
BMS 669 Neurobiology 3 hrs
BMS 661 Medical and Pathologic Physiology 4 hrs
BMS 727 Human Gross Anatomy 2 hrs
PAS 781 Advanced Pharmacotherapeutics 3 hrs
BIO 650 Statistical Methods for Biologists OR 3 hrs
MTH 645 Applied Statistics  OR  3 hrs
PSY 711 Introductory Statistics for Education and Psychology 3 hrs
    1. Clinical Core                                                  Total   38 hrs 

A clinical component is required.  This requirement may be met either by having passed the national certification examination for nurse anesthesia or by enrolling in the following courses.

Course CodeCourse TitleCredit Hours
ANE 702 Clinical Conference I 1 hr
ANE 705 Clinical Conference II 1 hr
ANE 708 Clinical Conference III 1 hr
ANE 711 Clinical Conference IV 1 hr
ANE 714 Orientation to Clinical Anesthesia 1 hr
ANE 720 Basic Principles of Anesthesia 3 hrs
ANE 726 Introduction to Clinical Anesthesia 2 hrs
ANE 732 Advanced Anesthesia Principle I 6 hrs
ANE 735 Clinical Practicum 16 hrs
ANE 744 Pharmacology in Anesthesia 2 hrs
ANE 750 Advanced Anesthesia Principles II 4 hrs
  1. Research Requirement (total 4 hours).  Each candidate will be assigned to a clinical research project.  The candidate must complete one seminar by enrolling in BMS 797, Non-Thesis Project (2 hrs) and a research involvement by enrolling in BMS 798, Research (2 hrs).  A formal presentation of the project is required.
  2. Students who are already a CRNA:  A certified registered nurse anesthetist (CRNA) may enter the program and must complete the core course requirements, the research requirements, and electives chosen in consultation with the student’s committee to total at least 33 hours.  CRNA students must provide a clinical transcript from their former anesthesia program.  Students must complete all cases/procedures that allow them to fulfill the minimum clinical requirements currently set forth by the Council on Accreditation.  At least 6 hours of clinical practicum, ANE 735, are required.
  3. Additional requirements or limitations.
    1. The candidate must maintain a minimum GPA of at least 3.00 each semester for the degree
    2. All requirements must be satisfied within eight years
    3. Matriculated students must enroll on a full-time basis and progress through the program with their class
    4. All course work must be approved by the Program Director or the Head of the Department of Biomedical Sciences
    5. The candidate must pass oral and written comprehensive examinations
    6. No more than 4 hours of C grade is allowed during the program
    7. No grade below a C grade will be allowed at any time during the program
    8. Candidates who do not achieve the academic standards set forth by the program will be immediately dismissed
    9. During the clinical phase, the student will carry liability insurance purchased through the AANA
    10. A $2200.00 program fee will be applied per each semester:  Fall, Spring and Summer

Dietetic Internship Certificate

Program Accreditation

The Missouri State University Dietetic Internship Certificate Program has been granted Candidacy for Accreditation by the Accreditation Council for Education in Nutrition and Dietetics (ACEND).  ACEND is the Academy of Nutrition and Dietetics' accrediting agency for education programs preparing students for careers as registered dietitians or dietetic technicians.  ACEND exists to serve the public by establishing and enforcing eligibility requirements and accreditation standards that ensure the quality and continued improvement of nutrition and dietetics education programs.  Program meeting those standards are accredited by ACEND.

Program Goals

The Dietetic Internship will:

  1. prepare graduates to be competent for practice as an entry-level dietitians.
  2. prepare graduates with life-long learning skills which will enhance the dietetic profession and demonstrate leadership in the field of dietetics.
  3. emphasize and model a commitment to community engagement and prepare graduates who are socially accountable.
Admission Requirements
  1. Evidence of meeting the minimum academic requirements from an ACEND-approved Didactic Program in Dietetics by a "Verification Statement" or "Declaration of Intent to Complete Degree" and/or ACEND-approved "Minimum Academic Requirements" within five years of application.
  2. Completion of the baccalaureate degree from an accredited college or university.
  3. Cumulative GPA of 3.00 over the last 60 hours of academic work taken.
  4. Graduate Record Examination (GRE) required taken no earlier than five years prior to application with a preferred minimum score of 150 in Verbal, 141 in Quantitative, and 4 in the Writing Sections.
  5. Completed application form.
  6. A personal philosophy statement not longer than 1,000 words that addresses the applicant's professional career goals and how the DI program will help accomplish these goals.
  7. Students for whom English is a second language must earn a minimum score of 600 (paper-based), 250 (computer-based), or 100 (internet-based) within two years prior to application on the Test of English as a Foreign Language (TOEFL).  The TOEFL website is http://www.toefl.org.
  8. Three written recommendations received with the application must be without significant reservations/concern.
    1. Dietetic academic reference
    2. Work or volunteer reference
    3. Final reference is the applicant’s choice
  9. Resume which includes:
    1. Work experience in dietetics, including number of hours of paid and volunteered work
    2. Involvement in college and/or community activities
  10. After the application period closes, the selection committee will review all of the applications and select students for an interview.  Personal interview are preferred, but if this is not possible, a phone interview can be arranged.  Interviews will be conducted at the Professional Building on the Missouri State University campus in Springfield, Missouri.
  11. Following admission to the Missouri State DI, interns will complete the Graduate College Application for Admission and be enrolled in the graduate college.
  12. After formal admission to the University and the program, interns will submit a completed Graduate Certificate Plan of Study.
Upon acceptance to the DI, additional requirements include:
  1. Meet technical standards of the program in order to successfully undertake the course of study including evidence of good health.  These standards are available upon request from the program.
  2. Evidence of immunization or vaccination for vaccine-preventable diseases to include MMR, tetanus, TB test, Hepatitis A, and a complete Hepatitis B series including a titer demonstrating immunity.  Other vaccinations may be required such as a seasonal flu vaccine.
  3. Evidence of professional liability and health insurance, including hospitalization.
  4. Provide documentation of negative tuberculosis status or evidence of appropriate follow-up.
  5. Hold and maintain infant, child and adult CPR certification valid throughout the DI.
  6. Hold SenSafe Certification valid throughout the DI.
  7. Interns must have reliable transportation and provide evidence of vehicle liability insurance that meets or exceeds the minimum requirements of the State of Missouri.
  8. Student membership in the AND.
  9. Interns must enroll on a full-time basis and progress through the program as a cohort group.
  10. Submit a drug screening test and criminal record check* and receive response that the applicant has not been convicted of any crime pursuant to Section 324.217 or other disqualifications that would prohibit licensure as a registered dietitian.

*Students who fail these checks or procedures will be subject to further review by the Department of Biomedical Sciences. 

Program Retention and Completion Requirements
  1. Interns must satisfactorily complete all assignments and experiences for each internship rotation.  Satisfactory completion will be based on performance appraisal which meets standards identified in appraisal rating criteria.
  2. Assignments or experiences which were not satisfactorily completed must be corrected or repeated.  No more than one graduate course may be repeated.
  3. Maintain a GPA of 3.00, with no more than 3 semester hours of graduate work below a grade of "B", and no hours of graduate work below a grade of "C".
  4. Receive a satisfactory (3) or higher rating in all required competencies as set forth by ACEND.
  5. Students must successfully complete all rotations and all course work in order to receive the verification statement and graduate certificate of completion.
  6. All work must be completed and competencies met within 150% (13.5 months) of the time planned for completion.

Required Courses

Course Code

Course Title

Credits

DTN 740

Medical Nutrition Therapy I Practicum

3 hrs

DTN 741

Medical Nutrition Therapy II Practicum

3 hrs

DTN 742

Public Health Nutrition Practicum

3 hrs

DTN 743

Food Service Management Practicum

3 hrs

DTN 744

Practicum in Area of Concentrations

3 hrs

DTN 745

Topics and Issues in Dietetics

3 hrs

 

Nurse Anesthesia Courses

ANE 702 Clinical Conference I

Review of significant cases involving complex anesthesia considerations.

ANE 705 Clinical Conference II

Prerequisite: ANE 702. A review of significant cases involving complex anesthesia considerations.

ANE 708 Clinical Conference III

Prerequisite: ANE 705. Continuing review of significant cases involving complex anesthesia considerations.

ANE 711 Clinical Conference IV

Prerequisite: ANE 708. Continuing review of significant cases involving complex anesthesia considerations.

ANE 714 Orientation to Clinical Anesthesia

Prerequisite: permission from program director. Introduction to anesthesia equipment, monitoring equipment, positioning, intravenous considerations, records, departmental management, ethics, departmental organization and function, legal and professional aspects.

ANE 717 Physics and Chemistry of Anesthesia

A presentation of the principles and laws of physics and chemistry applicable to the field of anesthesia.

ANE 720 Basic Principles of Anesthesia

A presentation of the principles of laws of physics and chemistry applicable to the field of anesthesia long with an in-depth analysis of structure and function of the cardiac, respiratory, circulatory, endocrine, hepatic, renal, neurologic, autonomic, and central nervous systems.

ANE 723 Application of Anatomy and Physiology to Anesthesia II

An in-depth analysis of the special relationships between anesthesiology and the endocrine, hepatatic, renal, neurologic, autonomic, and central nervous systems.

ANE 726 Introduction to Clinical Anesthesia

Preoperative evaluation of patients, airway management, inhalation techniques, common complications of induction and emergence. Supplemental course fee.

ANE 732 Advanced Anesthesia Principles I

Prerequisite: ANE 720. An in-depth review of drugs commonly used to provide the state of anesthesia, review of subjects essential to the practice of anesthesia; emphasis on pediatrics, neonatal, critical care anesthesia, trauma and burns, organ transplants and organ retrieval, obesity and GI disorders, and a study of the requirements for specialized anesthesia care; regional anesthesia, chronic pain, cardiac, and vascular anesthesia.

ANE 735 Clinical Practicum

Prerequisite: permission of instructor. Clinical experience in the anesthesiology department at Mercy. Specialty content may be included as part of the practicum experience. Section 4 taken in the fourth clinical semester includes specialty content related to professional/legal aspects of nurse anesthesia and cardiovascular anesthesia. May be repeated to a total of 26 hours. Graded Pass/Not Pass only. Supplemental course fee.

ANE 744 Pharmacology in Anesthesia

Prerequisite: ANE 720. A review of the effects of drugs required by patients with preexisting medical conditions and their continuation in the perioperative period.

ANE 750 Advanced Anesthesia Principles II

Prerequisite: ANE 720. A review of the special anesthetic considerations for: anesthesia delivery systems, pre-operative evaluation, monitoring, professional liability, rare and coexisting diseases, hemotherapy and hemostasis, post-anesthesia recovery, minimally invasive procedures, orthopedic, geriatric, outpatient anesthesia, airway management, respiratory physiology and function, thoracic surgery, neuro surgery, patients with liver and kidney disease, acid-base disturbances, and patients undergoing urologic, ophthalmic, and otolaryngologic surgery.

Biomedical Science Courses

BMS 602 Special Topics in Biomedical Sciences II

Prerequisite: permission of department head. Selected topics of an advanced nature which will vary from semester to semester. May be repeated by a student for a maximum of 8 hours of credit provided topics are different. May be taught concurrently with BMS 500. Cannot receive credit for both BMS 500 and BMS 602.

BMS 614 Scanning Electron Microscopy

An introduction to microsurface analysis using scanning electron microscopy and X-ray microanalysis. Theoretical considerations and laboratory procedures involve both techniques but the major emphasis will be on generation of secondary electron images. Some attention is devoted to backscattered electron imaging, X-ray mapping, stereo pair imaging, and related image processing techniques. May be taught concurrently with BMS 514. Cannot receive credit for both BMS 514 and BMS 614.

BMS 616 Transmission Electron Microscopy

Demonstration of basic transmission electron microscopy techniques and Microscope use. Emphasis is on ultrathin sectioning techniques; additional techniques include support film preparation, negative staining, immunogold localization procedures, and digital processing of photographic prints and negatives. May be taught concurrently with BMS 516 . Cannot receive credit for both BMS 516 and BMS 616.

BMS 620 Medical Cell Biology

Prerequisite: admission to the MS in Nurse Anesthesia program. Focus on the molecular aspects of cell biology for students in the Nurse Anesthesia program. Content identical to the lecture part of BMS 622. Cannot receive credit for both BMS 620 and 622. May be taught concurrently with BMS 520. Cannot receive credit for BMS 520 and BMS 620.

BMS 622 Molecular Cell Biology

Prerequisite: permission of instructor. Origins, structure and function of cells and basic life processes from a molecular perspective. Major topics focus on the energy, chemical, and information exchanges within and among cells and their environment. Cannot receive credit for both BMS 620 and 622. May be taught concurrently with BMS 521. Cannot receive credit for BMS 521 and BMS 622. Supplemental course fee.

BMS 624 Virology

Prerequisite: BMS 622. The molecular biology and pathogenicity of animal viruses; basic techniques of tissue culture and virology will be performed in the laboratory. May be taught concurrently with BMS 524. Cannot receive credit for BMS 524 and BMS 624.

BMS 625 Molecular Biology

Prerequisite: permission of the instructor. In-depth examination of nucleic acid structure, function, regulation, repair, and mutagenesis; principles of genetic engineering. Laboratory provides experience in the techniques used to isolate, separate, quantitate, characterize, and modify nucleic acids. The course also includes an introduction to the GenBank and EMBL nucleic acid and protein sequence databases. May be taught concurrently with BMS 525. Cannot receive credit for BMS 525 and BMS 625. Supplemental course fee.

BMS 628 Molecular Mechanisms of Bacterial Pathogenesis

Prerequisite: BMS 622. An in-depth study of the methods of genetic control and production of pathogenic factors employed by disease causing bacteria. The course will use both reference material and primary literature to illustrate the topics under discussion. May be taught concurrently with BMS 528. Cannot receive credit for both BMS 528 and BMS 628.

BMS 629 Molecular Genetics

Prerequisite: BMS 625. Recent advances in the molecular aspects of genetics; mammalian DNA will be characterized and manipulated using modern molecular techniques. May be taught concurrently with BMS 529. Cannot receive credit for both BMS 529 and BMS 629.

BMS 631 Cell Biology of Cancer

Prerequisite: BMS 622. Discussion of the initiation, cellular and genetic events which lead to cancer as well as its prevention, treatment, and personal consequences. An extensive paper and presentation are required. May be taught concurrently with BMS 530. Cannot receive credit for both BMS 530 and BMS 631.

BMS 635 Signal Transduction

Prerequisite: BMS 622. This course will examine the molecular mechanisms of various ligand/receptor interactions. The dynamics involved in ligand/receptor binding will be studied and examples of receptor-mediated signal transduction will be introduced. Signaling pathways within the cell will be discussed. Primary literature and reference materials will be utilized to illustrate specific examples under discourse. May be taught concurrently with BMS 535. Cannot receive credit for both BMS 535 and BMS 635.

BMS 640 Biotechnology

Prerequisite: permission of instructor. The applications of the methodologies of cell and molecular biology in the rapidly-evolving biotechnology and biopharmaceutical industries with an emphasis on the major sectors involving human therapeutics, human diagnostics, and genomics. Cell and molecular biology technologies adapted to mass production techniques to produce the products of biotechnology are surveyed. Typical pathways of product development from original basic research, product inception, clinical trials, regulatory approval, and commercialization are covered. Students will examine the current programs of the research and development of selected biotechnology and big pharmaco corporations. May be taught concurrently with BMS 540. Cannot receive credit for both BMS 540 and BMS 640.

BMS 658 Recombinant DNA Techniques

Prerequisite: C grade or better in BMS 625. A laboratory intensive course designed to extend the molecular biology principles and current techniques used in gene cloning, site-directed mutagenesis, transformation of eukaryotic cells, designing gene expression vectors, performing molecular hybridization techniques, confirming gene expression through reverse transcriptase PCR, and DNA sequencing. May be taught concurrently with BMS 558. Cannot receive credit for both BMS 558 and BMS 658.

BMS 660 Medical and Pathologic Physiology Laboratory

Prerequisite: admission to MS in Cell and Molecular Biology or MS in Nurse Anesthesia Program. Experience using laboratory techniques and case studies to enhance knowledge of pathophysiology. May be taught concurrently with BMS 562. Cannot receive credit for both BMS 562 and BMS 660.

BMS 661 Medical and Pathologic Physiology

Prerequisite: admission to MS in Cell and Molecular Biology or MS in Nurse Anesthesia Program. A study of physiological dysfunction in human disease with consideration of disease etiology, diagnosis, clinical interpretation, and treatment. Designed for students and professionals in the health sciences. May be taught concurrently with BMS 561. Cannot receive credit for both BMS 561 and BMS 661.

BMS 663 Advanced Work Physiology

Review of cellular metabolism, energy transfer, and oxygen transport during work; excitation-contraction coupling in skeletal muscle; physiological mechanisms of fatigue; neuroendocrine regulation of metabolism and other responses to work; environmental factors in work performance. Emphasis on molecular and cellular mechanisms and contemporary research. May be taught concurrently with BMS 563. Cannot receive credit for both BMS 563 and BMS 663.

BMS 664 Molecular Endocrinology and Reproductive Physiology

A detailed examination of the physiological, cellular and molecular aspects of human reproduction with particular emphasis on the endocrine aspects of reproduction. May be taught concurrently with BMS 564. Cannot receive credit for both BMS 564 and BMS 664.

BMS 665 Human Cardiopulmonary Physiology

Prerequisite: admission to MS in Cell and Molecular Biology or MS in Nurse Anesthesia program. A cellular and molecular study of human cardiovascular and respiratory physiology and related human diseases. Emphasis will be on the molecular mechanisms for normal and abnormal functions of the blood, the blood vessels, the heart, the respiratory tract, and the lung. Current research topics and results will be introduced and discussed. May be taught concurrently with BMS 565. Cannot receive credit for both BMS 565 and BMS 665.

BMS 667 Physiology of Exercise Metabolism

Introduction to the study of human metabolic and work physiology. Digestion, absorption, and metabolism of biologically important nutrients as they affect cellular energy transfer; mechanisms of energy transfer in cells during various forms of work; oxygen transport and utilization at the cellular and system level; factors modifying the efficiency of human work performance. May be taught concurrently with BMS 567. Cannot receive credit for both BMS 567 and BMS 667.

BMS 668 Physiology of the Human Gastrointestinal and Urinary Systems

Structure and function of the gastrointestinal and urinary systems including pathophysiology of common clinical conditions. May be taught concurrently with BMS 568. Cannot receive credit for both BMS 568 and BMS 668.

BMS 669 Neurobiology

Prerequisite: permission of instructor. Study of the mammalian nervous system including anatomy and principles of function. May be taught concurrently with BMS 569. Cannot receive credit for both BMS 569 and BMS 669.

BMS 670 Principles of Pharmacology

Prerequisite: permission of instructor. Recommended Prerequisite: BMS 622. Overview of the aspects of pharmacology including: pharmacodynamics, pharmacokinetics, pharmacogenomics, drug selectivity, toxicity, metabolism, drug development, and drug regulation. Additionally, an overview of the major classification of drugs and their mechanisms of action will be presented. May be taught concurrently with BMS 570. Cannot receive credit for both BMS 670 and BMS 570.

BMS 682 Embryology

Recommended Prerequisite: human anatomy. A study of anatomical changes during early animal development with emphasis on vertebrates. Lecture emphasis is on the cellular and subcellular mechanisms that may explain normal development, especially with regard to fertilization and morphogenesis. Laboratory emphasis on the normal development of live and preserved vertebrate embryos. Meets the embryology requirements for students in pre-professional medical, dental, and allied health curricula, as well as any student requiring a background in embryology. May be taught concurrently with BMS 582. Cannot receive credit for both BMS 582 and BMS 682.

BMS 686 Molecular Mechanisms in Animal Development

An overview of the relationship between the anatomy of developing embryos and fundamental molecular mechanisms that generate this morphology, with an emphasis on vertebrates. Some invertebrate systems will be presented. Selected topics will include cell signaling during fertilization, gene activity in early development, cytoskeleton dynamics during morphogenesis, cell-cell adhesion, master pattern genes, and regulated cell death. May be taught concurrently with BMS 584. Cannot receive credit for both BMS 584 and BMS 686.

BMS 688 Histology

Microscopic structure of cells, tissues, and organ systems, with special emphasis on human tissues. Extensive laboratory experience with interpretation of structures in stained tissues mounted on microslides. Recommended for students in medical, dental, optometric, and other preprofessional curricula, medical technology, cell and molecular biology, and zoology. May be taught concurrently with BMS 585. Cannot receive credit for both BMS 585 and BMS 688.

BMS 693 Bioinformatics and Biomedical Resources

Prerequisite: permission of instructor. Use of biomedical source materials and methods of data access, selection, organization, and evaluation. May be taught concurrently with BMS 593. Cannot receive credit for both BMS 593 and BMS 693.

BMS 700 Introduction to Graduate Studies in the Biomedical Sciences

Prerequisite: admission to MS in Nurse Anesthesia program. Study of the researcher role, the research process, and research ethics relating to the biomedical sciences.

BMS 701 Research in the Biomedical Sciences

Prerequisite: admission to MS in Cell and Molecular Biology program; and statistics: MTH 645 or BIO 650 or PSY 711 or concurrent enrollment in statistics. Focus on research skills, scientific writing, and professional development.

BMS 707 Medical Human Anatomy

Prerequisite: admission to Doctor of Physical Therapy program. This course offers an in-depth coverage of basic, applied, and clinical aspects of gross anatomy. Students observe, discuss, teach, learn, and dissect all body systems in detail. This course incorporates traditional didactic lectures, discussions, laboratory dissection, students teaching students in laboratory teaching sessions, and assignments that rely on critical thinking. Students make oral presentations and use the library and other sources of information (such as the internet and our Computer Laboratory) to learn and teach applied gross anatomy. Identical with PTE 707. Cannot receive credit for both BMS 707 and PTE 707. Supplemental course fee.

BMS 711 Microbial Genetics

Prerequisite: BMS 622. Course is designed to investigate various aspects of microbial genetics using advanced laboratory techniques. Experiments may include DNA and plasmid isolation and characterization, mutagenesis, transformation, transduction and conjugation of bacteria.

BMS 717 Medical Human Anatomy and Radiology

Prerequisite: admission to the Physician Assistant Studies program. Regional study of the human body. Course will include lecture and laboratory activities including cadaver dissection, study of anatomic models, computer images, x-ray, CAT scan and MRI, and ultrasound imaging. Identical with PAS 717. Cannot receive credit for both BMS 717 and PAS 717. Supplemental course fee.

BMS 726 Advanced Topics in Cell and Molecular Biology

Prerequisite: permission of instructor. Focused or detailed consideration of advanced or timely topics in cell and molecular biology. May involve group discussion from another institution or represent individual study. Credit for BMS 726 may be given for electronic and distance learning courses available via the Internet with the approval of the cell and molecular biology faculty who will determine the credit hours and topic title. Variable content course. May be repeated up to 6 hours when topic varies.

BMS 727 Human Gross Anatomy

Prerequisite: admission to MS in Nurse Anesthesia program. In-depth study of the gross anatomy of the human body in areas of interest relating to administration of anesthesia. Supplemental course fee.

BMS 730 Current Literature Topics

Prerequisite: admission to MS in Cell and Molecular Biology program. A weekly forum of faculty and graduate students to discuss reports in the current literature from cell, molecular, and developmental biology. Participants are assigned to report on developments in their specialty or area of interest and provide background for understanding the basis and significance of the report to others in the group. May be repeated. Required each regular semester for full time students.

BMS 732 Clinical Preventive Medicine

Prerequisite: permission of instructor. A review of current scientific evidence regarding effective screening tests and interventions to improve health status.

BMS 752 Medical Physiology

Prerequisite: admission to Physician Assistant Studies program or Doctor of Physical Therapy program or MS in Cell and Molecular Biology program. The study of biological function of the human organism. Emphasis will be placed on mechanisms and regulation using examples focusing on the field of medicine. Topics covered will include general cell function, neural, endocrine, cardiovascular, respiratory, gastrointestinal and renal physiology and regulation of acid-base balance. The course stresses the interrelated functions of the body systems in homeostasis and builds on this knowledge to introduce how disease alters the homeostatic controls.

BMS 784 Developmental Genetics

Prerequisite: BMS 625. A study of developmental gene families, their expressions as related to the normal and abnormal development of form and structure, and their intrinsic and extrinsic regulation in various animal model systems, including humans. Specific gene-programmed and gene regulated mechanisms such as those regulating pattern formation, triggering cell differentiation, initiating regeneration (as it applies to specific tissues and organs), controlling apoptosis, and determining rates of cellular and organismal aging are included.

BMS 785 Histology and Tissue Biology

Prerequisite: admission to MS in Nurse Anesthesia program or MS in Cell and Molecular Biology program. This course emphasizes the structure and basic function of all the major tissues and cell types in the human body. It includes normal cell and tissue morphology and the adaptations that occur as a result of various stimuli both normal and abnormal.

BMS 797 Non-Thesis Project

Prerequisite: permission of instructor. In-depth study in an area of interest, culminating in a presentation of an extensive scholarly paper. Graded Pass/Not Pass Only.

BMS 798 Research

Prerequisite: permission of instructor. Application of the research process in the supervised study of a selected problem. May be repeated for a maximum of 6 hours. Graded Pass/Not Pass only.

BMS 799 Thesis

Prerequisite: permission of instructor. Demonstration of the capacity for research and independent thought culminating in a thesis. May be repeated for a maximum of 6 hours. Graded Pass/Not Pass only.

Dietetics and Nutrition Courses

DTN 740 Medical Nutrition Therapy I Practicum

Prerequisite: admission to the graduate Dietetic Internship Certificate Program. This is the first of a two-semester course sequence providing field experience in patient/client nutritional management at various sites under professional supervision (37 hours per week). Emphasis will be on utilizing the nutrition care process in providing basic medical nutrition therapy to include at least diabetes, heart disease, lung disease and basic health promotion in an acute or clinical setting.

DTN 741 Medical Nutrition Therapy II Practicum

Prerequisite: admission to the graduate Dietetic Internship Certificate Program. This is the second of a two-semester course sequence providing eight weeks of field experience in patient/client nutritional management at various sites under professional supervision (40 hours per week). Emphasis will be on utilizing the nutrition care process in providing medical nutrition therapy to include at least tube feeding, TPN, pre/post surgery patients in an acute or clinical setting with a research component required as part of the practicum.

DTN 742 Public Health Nutrition Practicum

Prerequisite: admission to the graduate Dietetic Internship Certificate Program. This course provides a six week field experience in the delivery of public health and community nutrition programs at local, state, national levels at various sites under professional supervision (37 hours per week). Current issues relating to the promotion of good nutrition and preventive health care will be examined. Students will evaluate nutrition components of various community health agencies and participate in the delivery of services.

DTN 743 Food Service Management Practicum

Prerequisite: admission to the graduate Dietetic Internship Certificate Program. This course provides a six week field experience (37 hours per week) practicing a systems approach to nutrition services management, including the human dimensions of management, management tools and techniques for assessing accountability, cost containment, productivity and marketing plans. Projects include development of a personnel and operational budget for nutrition services.

DTN 744 Practicum in Area of Concentration

Prerequisite: admission to the graduate Dietetic Internship Certificate Program. This course provides a six week field experience (40 hours per week) in either Public Affairs or Rural Health. Field placements and experiences will be developed with each student and the program director.

DTN 745 Topics and Issues in Dietetics

Prerequisite: admission to the graduate Dietetic Internship Certificate Program. This course provides a six week forum (3 hours per week) for topics pertinent to the practice setting and transition to professional practice. Topics of interest will cover areas such as managed health care, ethical decision-making, registration examination, charting, etc. May be repeated to 3 hours.